Phenol → HCID 66716929, compound

Participants

Reaction Steps

Using 4-((2H-indazol-2-yl)methyl)-2-nitrophenol as the phenol and methyl-2-bromopropanoate as the alkylating agent in the general procedure for alkylation of substituted-2-nitrophenols gives a light yellow solid: 1H NMR (400 MHz, DMSO-d6) δ ppm 1.51 (d, J=6.82 Hz, 3H) 3.66 (s, 3H) 5.24 (q, J=6.82 Hz, 1H) 5.66 (s, 2H) 7.00-7.08 (m, 1H) 7.19-7.29 (m, 2H) 7.54-7.63 (m, 2H) 7.71 (d, J=8.34 Hz, 1H) 7.94 (d, J=2.02 Hz, 1H) 8.52 (s, 1H). ESI-MS: m/z 356.2 (M+H)+.

Provenance & Evidence