Ammonia → HCID 89466349, compound

Participants

Reaction Steps

A mixture of Example 96A (265 mg, 0.883 mmol), 7 M ammonia in methanol (5.00 mL) and Raney®-nickel (2800, water slurry, 530 mg, 9.03 mmol) in a 50 mL pressure bottle was stirred for 16 hours under hydrogen (30 psi) at room temperature. The mixture was filtered through a nylon membrane, and the filtrate was concentrated to give the titled compound. LCMS (APCI) m/z 287 (M+H)+.

Provenance & Evidence