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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1184621Generated: October 29, 2026

Ethylamine → HCID 86680540, compound

https://huagongshe.com/reaction/1184621

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthylamineHCID 6341—
ReactantTrifluoroacetic acidHCID 6422—
Reactant3,3-DifluoropyrrolidineHCID 2782827—
ReactantHCID 86680539HCID 86680539—
ProductHCID 86680540HCID 86680540—

Reaction Steps

The title compound was prepared as a trifluoroacetic acid salt according to the procedure described in Example 194B, substituting the product from Example 179A for the product from Example 194A, and substituting 3,3-difluoropyrrolidine for ethylamine. 1H NMR (300 MHz, CDCl3) δ ppm 0.88-1.07 (m, 4 H) 5.37-5.59 (m, 2 H) 7.57-7.73 (m, 3 H) 7.75-7.87 (m, 1 H) 7.89-7.96 (m, 1 H) 7.98-8.12 (m, 1 H); MS (ESI) m/z 552 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08669255B2
Source datasetuspto-grants-2014_03
ORD IDord-0da7226ab27841bba6085119690d4ed3
Source noteuspto-grants-2014_03