HCID 86680529, compound → HCID 86680543, compound

Participants

Reaction Steps

A solution of the product from Example 181 (0.132 g, 0.235 mmol) in 1,4-dioxane (1 mL) and 4 N HCl in 1,4-dioxane (1 mL, 4.00 mmol) was stirred at room temperature for 90 minutes and then concentrated in vacuo to give the title compound as a hydrochloride salt. 1H NMR (500 MHz, DMSO-d6) δ ppm 0.76-1.01 (m, 4 H) 1.86-4.94 (m, 12 H) 5.25-5.56 (m, 1 H) 5.70-6.01 (m, 1 H) 7.79 (d, J=6.41 Hz, 2 H) 7.85-7.98 (m, 2 H) 8.09-8.24 (m, 2 H) 8.78-9.11 (m, 3 H) 11.73-12.34 (m, 1 H); MS (APCI) m/z 462 (M+H)+.

Provenance & Evidence