化工社化工社 化学情報印刷レポート · 研究参考用
Thiophenol → S-Phenyl 2-(2-naphthyl)ethanethioate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Thiophenol | HCID 7969 | — |
| 反応物 | Triethylamine | HCID 8471 | — |
| 反応物 | 2-(2-Naphthyl)acetyl chloride | HCID 588115 | — |
| 反応物 | Isohexane ethyl acetate | HCID 21882781 | — |
| 溶媒 | Toluene | HCID 1140 | — |
| 生成物 | S-Phenyl 2-(2-naphthyl)ethanethioate | HCID 86656471 | 90% |
反応手順
2-(2-Naphthyl)acetyl chloride (308 mg, 1.5 mmol) in 4.5 mL toluene was added to a solution of triethylamine (0.21 mL, 1.5 mmol) and thiophenol (153 μL, 1.5 mmol) in 3 mL toluene. Reaction monitoring was accomplished by TLC: iso-hexane/ethyl acetate 25:1, Rf=0.33. Workup yielded 376 mg (90%) S-phenyl 2-(2-naphthyl)ethanethioate 9 as yellow solid.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08669283B2 |
| 出典データセット | uspto-grants-2014_03 |
| ORD ID | ord-942f4611a8024f368e75d857f8d7bdc4 |
| 出典メモ | uspto-grants-2014_03 |