1-(Ethanesulfonyl)piperazine → HCID 71115030, compound

HRID 1184788Notes

Reaction equation

HRID 1184788 reaction equation
[C:1]([O:5][C:6]([N:8]1[CH2:13][CH2:12][CH:11]([CH:14]2[O:23][C:17]3=[CH:18][N:19]=[C:20](Cl)[CH:21]=[C:16]3[CH2:15]2)[CH2:10][CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2].[CH2:24]([S:26]([N:29]1[CH2:34][CH2:33][NH:32][CH2:31][CH2:30]1)(=[O:28])=[O:27])[CH3:25]>>[C:1]([O:5][C:6]([N:8]1[CH:13]=[CH:12][C:11]([CH:14]2[O:23][C:17]3=[CH:18][N:19]=[C:20]([N:32]4[CH2:31][CH2:30][N:29]([S:26]([CH2:24][CH3:25])(=[O:27])=[O:28])[CH2:34][CH2:33]4)[CH:21]=[C:16]3[CH2:15]2)=[CH:10][CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2]

Participants

3

Reactant 2

HCID 4152941-(Ethanesulfonyl)piperazineHCID 866748954-(5-Chloro-2,3-dihydrofuro[2,3-c]pyridin-2-yl)piperidine-1-carboxylic acid tert-butyl ester

Product 1

HCID 71115030HCID 71115030, compound

Procedure

The title compound is prepared from 4-(5-chloro-2,3-dihydro-furo[2,3-c]pyridin-2-yl)-piperidine-1-carboxylic acid tert-butyl ester and 1-(ethylsulfonyl)piperazine following a procedure analogous to that described in Example 79. LC (method 10): tR=1.45 min;

Sources & evidence

ORD record
ord-db6e0bf6b1c447fb8a71930e6323571d
Source dataset
uspto-grants-2014_03
Patent number
US08669271B2

Reaction notes

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