HCID 20569916, compound → HCID 71115041, compound

HRID 1184791Notes

Reaction equation

HRID 1184791 reaction equation
[C:1]([O:5][C:6]([N:8]1[CH2:13][CH2:12][CH:11]([CH:14]2[O:23][C:17]3=[CH:18][N:19]=[C:20](Br)[CH:21]=[C:16]3[CH2:15]2)[CH2:10][CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2].[CH3:24][N:25]([CH:30]1[CH2:35][CH2:34][NH:33][CH2:32][CH2:31]1)[S:26]([CH3:29])(=[O:28])=[O:27]>>[C:1]([O:5][C:6]([N:8]1[CH2:13][CH2:12][CH:11]([CH:14]2[O:23][C:17]3=[CH:18][N:19]=[C:20]([N:33]4[CH2:32][CH2:31][CH:30]([N:25]([S:26]([CH3:29])(=[O:27])=[O:28])[CH3:24])[CH2:35][CH2:34]4)[CH:21]=[C:16]3[CH2:15]2)[CH2:10][CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2]

Participants

3

Reactant 2

HCID 20569916HCID 20569916, compoundHCID 86674903HCID 86674903, compound

Product 1

HCID 71115041HCID 71115041, compound

Procedure

The title compound is prepared from 4-(5-bromo-2,3-dihydro-furo[2,3-c]pyridin-2-yl)-piperidine-1-carboxylic acid tert-butyl ester and N-methyl-N-piperidin-4-ylmethanesulfonamide following a procedure analogous to that described in Example 79. LC (method 10): tR=1.35 min; Mass spectrum (ESI+): m/z=495 [M+H]+.

Sources & evidence

ORD record
ord-0dc136dd39ac444b99671492637495c5
Source dataset
uspto-grants-2014_03
Patent number
US08669271B2

Reaction notes

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