HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 2-Ethoxythieno[2,3-b]pyrazine-6-carbonyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 2-Ethoxythieno[2,3-b]pyrazine-6-carboxylic acid | HCID 67125582 | — |
| Product | 2-Ethoxythieno[2,3-b]pyrazine-6-carbonyl chloride | HCID 86680184 | 100% |
Reaction Steps
A solution of 2-ethoxythieno[2,3-b]pyrazine-6-carboxylic acid (30 mg, 0.134 mmol) in thionyl chloride (1 mL) was stirred at 80° C. for 2 h. Evaporated to dryness and co-evaporated with toluene to give 2-ethoxythieno[2,3-b]pyrazine-6-carbonyl chloride (32 mg, 100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08669256B2 |
| Source dataset | uspto-grants-2014_03 |
| ORD ID | ord-a4ab962234864a819bf86d7102c66b68 |
| Source note | uspto-grants-2014_03 |