HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-tert-Butylbenzoic acid → 4-tert-Butylbenzoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-tert-Butylbenzoic acid | HCID 7403 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Product | 4-tert-Butylbenzoyl chloride | HCID 74372 | — |
Reaction Steps
A mixture of 4-tert-butylbenzoic acid (1000 g, 5.6 mol) in sulfurous dichloride (1.5 L) was refluxed for 3 hours. Then the mixture was concentrated in vacuo, and the crude 101a was used in next step without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08669251B2 |
| Source dataset | uspto-grants-2014_03 |
| ORD ID | ord-a86621ed555145a8ac93ae10ffe1f505 |
| Source note | uspto-grants-2014_03 |