HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-chloro-1-methyl-4-nitro-1H-pyrazole → 4,4-difluoro-1-(1-methyl-4-nitro-1H-pyrazol-5-yl)azepane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-chloro-1-methyl-4-nitro-1H-pyrazole | HCID 12344836 | — |
| Reactant | 4,4-Difluoroazepane | HCID 53393482 | — |
| Product | 4,4-difluoro-1-(1-methyl-4-nitro-1H-pyrazol-5-yl)azepane | HCID 58464884 | 100% |
Reaction Steps
Reaction of 5-chloro-1-methyl-4-nitro-1H-pyrazole and 4,4-difluoroazepane gave 4,4-difluoro-1-(1-methyl-4-nitro-1H-pyrazol-5-yl)azepane as a white solid (0.41 g, 100%). 1H NMR (400 MHz, CDCl3) δ 8.04 (s, 1H), 3.79 (s, 3H), 3.39-3.23 (m, 4H), 2.35-2.20 (m, 4H), 2.00-1.92 (m, 2H)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08669361B2 |
| Source dataset | uspto-grants-2014_03 |
| ORD ID | ord-7e9e6fa3dde343f18062b190ec341325 |
| Source note | uspto-grants-2014_03 |