HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-((R)-1-Benzyloxycarbonyl-ethoxy)-7-methyl-quinoline-2-carboxylic acid methyl ester → HCID 68598842, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-((R)-1-Benzyloxycarbonyl-ethoxy)-7-methyl-quinoline-2-carboxylic acid methyl ester | HCID 68599301 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 68598842 | HCID 68598842 | — |
Reaction Steps
To a solution of 1.80 g 4-((R)-1-Benzyloxycarbonyl-ethoxy)-7-methyl-quinoline-2-carboxylic acid methyl ester in 15 ml ethanol were added 200 mg Pd/C (10%) and the suspension stirred under an atmosphere of hydrogen (5 bar) for 18 h. Then, the reaction mixture was filtrated over a plug of Celite®, washed with ethanol and concentrated. Yield: 1.30 g colorless oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08669266B2 |
| Source dataset | uspto-grants-2014_03 |
| ORD ID | ord-4bea7739ecdf4ec59496e823a39e4f39 |
| Source note | uspto-grants-2014_03 |