HuagongsheHuagongshe Chemistry Print Report · For research reference only
(S)-2-(1-Benzyl-1H-tetrazol-5-yl)-pyrrolidine-1-carboxylic acid benzyl ester → HCID 178420796, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (S)-2-(1-Benzyl-1H-tetrazol-5-yl)-pyrrolidine-1-carboxylic acid benzyl ester | HCID 66857129 | — |
| Catalyst | Palladium hydroxide | HCID 9942167 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 178420796 | HCID 178420796 | — |
Reaction Steps
To a solution of 494 mg (S)-2-(1-Benzyl-1H-tetrazol-5-yl)-pyrrolidine-1-carboxylic acid benzyl ester in 50 ml ethanol were added 100 mg Pd(OH)2/C (10%) and the suspension stirred under an atmosphere of hydrogen (4 bar) for 6 h. The reaction mixture was filtrated over a plug of Celite® and washed with ethanol. Yield: 173 mg colorless foam.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08669266B2 |
| Source dataset | uspto-grants-2014_03 |
| ORD ID | ord-87d8ecc7386a4cfa8c252337990800f4 |
| Source note | uspto-grants-2014_03 |