HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 68600019, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 68601180 | HCID 68601180 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 68600019 | HCID 68600019 | — |
Reaction Steps
To a solution of 463 mg (2S,4S)-2-Cyclobutylcarbamoyl-4-hydroxy-pyrrolidine-1-carboxylic acid tert-butyl ester in 8 ml dichloromethane were added 1.2 ml TFA. After 5 h stirring at RT the solvents were removed and the residue was codistilled twice with toluene. Yield: 463 mg.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08669266B2 |
| Source dataset | uspto-grants-2014_03 |
| ORD ID | ord-dd004e0bd9c44b7ba89be9115b71fa55 |
| Source note | uspto-grants-2014_03 |