Acetic Acid → Methyl 2-isopropylhydrazinecarboxylate

HRID 1185830Notes

Reaction equation

HRID 1185830 reaction equation
[CH3:1][O:2][C:3]([NH:5][N:6]=[C:7]([CH3:9])[CH3:8])=[O:4].C(O)(=O)C>C(O)C>[CH3:1][O:2][C:3]([NH:5][NH:6][CH:7]([CH3:9])[CH3:8])=[O:4]

Participants

4

Reactant 2

HCID 176Acetic AcidHCID 9095211-Methoxycarbonyl-2-isopropylidene hydrazine

Product 1

HCID 57863323Methyl 2-isopropylhydrazinecarboxylateYield 77.6%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

N′-Isopropylidene-hydrazine-carboxylic acid methyl ester (6.45 g) were dissolved in ethanol (50 mL) and acetic acid (50 mL) PtO2 (0.231 g) was added, and reaction was stirred at room temperature for 22 hours under an atmosphere of hydrogen. Mixture was evaporated under vacuum, giving N′-Isopropyl-hydrazine-carboxylic acid methyl ester (5.08 g, 77%) as a white solid.

Workup

  1. customreaction
  2. customMixture was evaporated under vacuum

Sources & evidence

ORD record
ord-566096ad66b14c7b9313cca7cc3c921a
Source dataset
uspto-grants-2014_03
Patent number
US08669234B2

Reaction notes

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