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HRID1185851

反应详情

EQUATION

反应方程式

HRID 1185851 的结构方程式

REACTANTS

反应物

2
结构：COC(=O)NC(C(=O)N1CCCC1c1ncc(-c2ccc(Br)cc2)[nH]1)C(C)C
HCID66620141

未命名化合物

2 次

结构：C#Cc1ccc(-c2cnc(C3CCCN3C(=O)C(NC(=O)OC)C(C)C)[nH]2)cc1
HCID72338228

未命名化合物

PRODUCTS

生成物

1
结构：C#Cc1ccc(-c2cnc(C3CC4(CC4)CN3C(=O)C(NC(=O)OC)C(C)C)[nH]2)cc1
HCID86648888

未命名化合物

PROCEDURE

实验过程

Title compound was prepared according to the method employed to prepare (1-{2-[5-(4-Ethynyl-phenyl)-1H-imidazol-2-yl]-pyrrolidine-1-carbonyl}-2-methyl-propyl)-carbamic acid methyl ester from (1-{2-[5-(4-bromo-phenyl)-1H-imidazol-2-yl]-pyrrolidine-1-carbonyl}-2-methyl-propyl)-carbamic acid methyl ester (Example AY), substituting (1-{6-[5-(4-Bromo-phenyl)-1H-imidazol-2-yl]-5-aza-spiro[2.4]heptane-5-carbonyl}-2-methyl-propyl)-carbamic acid methyl ester for (1-{2-[5-(4-bromo-phenyl)-1H-imidazol-2-yl]-pyrrolidine-1-carbonyl}-2-methyl-propyl)-carbamic acid methyl ester.