Tetrahydrofuran → HCID 67288189, compound

Participants

Reaction Steps

The obtained 2,4-dinitrophenylpropanoic acid methyl ester (2.29 g) was added into tetrahydrofuran (50 ml), and was dissolved by stirring at room temperature. Sodium borohydride (0.76 g, 0.02 mole) and aluminum trichloride (1.33 g, 0.01 mole) were then added, and reaction was conducted for 2 hours at room temperature. After the reaction, water (10 ml) was added to completely react with the remaining reductant. Solvent was removed by distilling under a reduced pressure to obtain 2,4-diaminophenylpropanoic acid methyl ester (1.67 g, yield: 86%).

Provenance & Evidence