N-(azetidin-3-ylcarbamoylmethyl)-3-trifluoromethyl-benzamide → N-({1-[4-(6-Oxo-1,6-dihydro-pyridin-2-yl)-cyclohexyl]-azetidin-3-ylcarbamoyl}-methyl)-3-trifluoromethyl-benzamide

HRID 118599Notes

Reaction equation

HRID 118599 reaction equation
[NH:15]1[CH2:16][CH:17]([NH:19][C:20](=[O:21])[CH2:22][NH:23][C:24]([c:25]2[cH:26][c:27]([C:31]([F:32])([F:33])[F:34])[cH:28][cH:29][cH:30]2)=[O:35])[CH2:18]1.[O:1]=[C:2]1[CH2:3][CH2:4][CH:5]([c:8]2[cH:9][cH:10][cH:11][c:12](=[O:14])[nH:13]2)[CH2:6][CH2:7]1>>[CH:2]1([N:15]2[CH2:16][CH:17]([NH:19][C:20](=[O:21])[CH2:22][NH:23][C:24]([c:25]3[cH:26][c:27]([C:31]([F:32])([F:33])[F:34])[cH:28][cH:29][cH:30]3)=[O:35])[CH2:18]2)[CH2:3][CH2:4][CH:5]([c:8]2[cH:9][cH:10][cH:11][c:12](=[O:14])[nH:13]2)[CH2:6][CH2:7]1

Participants

3

Reactant 2

HCID 59361594N-(azetidin-3-ylcarbamoylmethyl)-3-trifluoromethyl-benzamideHCID 595417636-(4-oxo-cyclohexyl)-1H-pyridin-2-one

Product 1

HCID 46946449N-({1-[4-(6-Oxo-1,6-dihydro-pyridin-2-yl)-cyclohexyl]-azetidin-3-ylcarbamoyl}-methyl)-3-trifluoromethyl-benzamide

Sources & evidence

ORD record
ord-d7ad393bfaf64ca0b99edff1ba384070
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

Loading…