Trifluoroacetic acid methylene chloride → HCID 71245312, compound

Participants

Reaction Steps

To a solution of compound 2 (1 g, 2.30 mmol) in CH2Cl2 (5 mL) was added 20% TFA-DCM (10 mL) and stirred at RT for 2 h. The reaction mixture was diluted with water (10 mL) and extracted with EtOAc (2×15 mL). The organic layer was dried over anhydrous Na2SO4 and concentrated under reduced pressure to yield compound 3 (800 mg, 92%).

Provenance & Evidence