Ammonia → HCID 70557038, compound

HRID 1186024Notes

Reaction equation

HRID 1186024 reaction equation
[NH3:1].[CH2:2]([C:17]1[CH:27]=[CH:26][C:20]([CH2:21][P:22](=[O:25])([OH:24])[OH:23])=[CH:19][CH:18]=1)[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16]>CO.CO.CCO>[NH3:1].[CH2:2]([C:17]1[CH:18]=[CH:19][C:20]([CH2:21][P:22](=[O:23])([OH:25])[OH:24])=[CH:26][CH:27]=1)[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16]

Participants

5

Reactant 2

HCID 222AmmoniaHCID 59054073HCID 59054073, compound2×

Product 1

HCID 70557038HCID 70557038, compoundYield 100%

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 18681192Ethanol, mixt. with methanolSolvent

Procedure

4-Pentadecylbenzyl phosphonic acid, ammonia salt was obtained by the following procedure: 2M NH3 in MeOH (0.8 mL) was added to a solution of 4-pentadecylbenzyl phosphonic acid (compound 22, 0.050 g) in MeOH-EtOH (4/1 mL) and the reaction mixture was stirred for 2 h at room temperature and TLC showed the completion of the reaction. The solvents were evaporated under reduced pressure to obtain pure 4-pentadecylbenzyl phosphonic acid ammonia salt as white powder (100% yield). MS(ESI) m/z 381 [M−H]−. Anal calcd. For C22H42NO3P: C, 66.13; H, 10.60; N, 3.51. Found C, 66.37; H, 10.60; N, 3.58.

Workup

  1. customthe completion of the reaction
  2. customThe solvents were evaporated under reduced pressure

Sources & evidence

ORD record
ord-91572299a94a41229e0203c4a6a86a0c
Source dataset
uspto-grants-2014_03
Patent number
US08673882B2

Reaction notes

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