反应详情

Sodium borohydride (111 mg) was added to the compound (400 mg) prepared in Example 4 in methanol solution (10 mL) and stirred for 1 hour at room temperature. The reaction mixture was concentrated and extracted with 1 mol/L hydrochloric acid and ethyl acetate. The organic layer was washed with saturated sodium and dried by anhydrous sodium sulfate, and then concentrated to obtain the titled compound (400 mg) having the following physical data.

1. concentrationThe reaction mixture was concentrated
2. extractionextracted with 1 mol/L hydrochloric acid and ethyl acetate
3. washThe organic layer was washed with saturated sodium
4. dry with materialdried by anhydrous sodium sulfate
5. concentrationconcentrated