HCID 67060824, compound → HCID 136414054, compound

HRID 1186100Notes

Reaction equation

[Cl:1][C:2]1[CH:39]=[CH:38][C:5]2[N:6](CC3C=CC(OC)=CC=3)[C:7](=[O:28])[C@@H:8]([CH2:20][C:21]3[CH:26]=[CH:25][CH:24]=[CH:23][C:22]=3[Cl:27])[N:9]=[C:10]([C:11]3[CH:16]=[CH:15][C:14]([O:17]C)=[C:13]([CH3:19])[CH:12]=3)[C:4]=2[CH:3]=1.ClC1C=CC2NC(=O)[C@@H](CC3C=CC=CC=3Cl)N=C(C3C=CC(OC)=C(C)C=3)C=2C=1>>[Cl:1][C:2]1[CH:39]=[CH:38][C:5]2[NH:6][C:7](=[O:28])[C@@H:8]([CH2:20][C:21]3[CH:26]=[CH:25][CH:24]=[CH:23][C:22]=3[Cl:27])[N:9]=[C:10]([C:11]3[CH:16]=[CH:15][C:14]([OH:17])=[C:13]([CH3:19])[CH:12]=3)[C:4]=2[CH:3]=1

Participants

Reactant 2

HCID 67060824HCID 67060824, compound

HCID 70664325HCID 70664325, compound

Product 1

HCID 136414054HCID 136414054, compound

Procedure

Physical Characterization Data for Synthetic Intermediate Compounds: (R)-7-Chloro-3-(2-chlorobenzyl)-5-(4-methoxy-3-methylphenyl)-1-(4-methoxybenzyl)-1H-benzo[e][1,4]diazepin-2(3H)-one. MS (m/z): 559.3 (M+1)+; and (R)-7-Chloro-3-(2-chlorobenzyl)-5-(4-methoxy-3-methylphenyl)-1H-benzo[e][1,4]diazepin-2(3H)-one. MS (m/z): 439.2 (M+1)+.

Sources & evidence

ORD record: ord-020e51d13b0547bc806e59d606f2721c
Source dataset: uspto-grants-2014_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08673897B2

Reaction notes

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