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HRID1186200

反应详情

EQUATION

反应方程式

HRID 1186200 的结构方程式

REACTANTS

反应物

2
结构：CC(C)Oc1ccc(C(=O)O)nc1
HCID21897735

5-[(Propan-2-yl)oxy]pyridine-2-carboxylic acid

C9H11NO3

结构：C[C@]1(c2cc(N)ccc2F)N=C(N)COCC1(F)F
HCID58562966

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)Oc1ccc(C(=O)Nc2ccc(F)c([C@@]3(C)N=C(N)COCC3(F)F)c2)nc1.O=CO
HCID54578010

未命名化合物

PROCEDURE

实验过程

The coupling of (R)-5-(5-amino-2-fluorophenyl)-6,6-difluoro-5-methyl-2,5,6,7-tetrahydro-1,4-oxazepin-3-amine (intermediate A10A) and 5-isopropoxy-pyridine-2-carboxylic acid (prepared according to Nagase, T. et al., Patent Application Publ. No. US20100249147) yielded the title compound as an off-white solid. MS (ISP): m/z=437.2 [M+H]+.