Potassium Carbonate → 2-chloro-N-(3-chloro-6,7-dimethylquinoxalin-2-yl)benzenesulfonamide

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Reaction Steps

According to Example 132, by use of 2,3-dichloro-6,7-dimethylquinoxaline (Compound HC) (300 mg, 1.32 mmol), dimethyl sulfoxide (5 mL), 2-chlorobenzenesulfonamide (253 mg, 1.32 mmol) and potassium carbonate (182 mg, 1.32 mmol), the mixture was stirred and reacted at 150° C. for 2 hours. Then, slurry purification was performed using diisopropyl ether, to give 2-chloro-N-(3-chloro-6,7-dimethylquinoxalin-2-yl)benzenesulfonamide (360 mg, yield: 71%).

Provenance & Evidence