HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 67401954, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | (Trifluoromethyl)trimethylsilane | HCID 552549 | — |
| Reactant | 2-Chloro-1,3-thiazole-5-carbaldehyde | HCID 1479765 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 67401954 | HCID 67401954 | — |
Reaction Steps
According to Reference Example 8-2, by use of 2-chlorothiazole-5-carbaldehyde (300 mg, 2.03 mmol) dissolved in N,N-dimethylformamide (4 mL), potassium carbonate (56 mg, 0.41 mmol) and (trifluoromethyl)trimethylsilane (0.360 mL, 2.44 mmol), the mixture was stirred and reacted at room temperature for 1.3 hours. Then, purification by preparative thin-layer chromatography (chloroform/methanol=15/1) was performed to give
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08673908B2 |
| Source dataset | uspto-grants-2014_03 |
| ORD ID | ord-9fb403dcf9c6448d8721f7ff0532fff1 |
| Source note | uspto-grants-2014_03 |