4-Aminotetrahydropyran → HCID 66548086, compound

Participants

Reaction Steps

Isopropyl-{3-[2-(tetrahydro-pyran-4-ylamino)-pyrimidin-4-yl]-imidazo[1,2-a]pyrazin-8-yl}-amine was prepared by a process analogous to that described in Example 12 starting from isopropyl-[3-(2-methylsulfanyl-pyrimidin-4-yl)-imidazo[1,2-a]pyrazin-8-yl]-carbamic acid tert-butyl ester (from Example 11 supra), and 4-amino-tetrahydropyran. LC-MS: [M+H]+ 354.3.

Provenance & Evidence