HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isopropylamine → HCID 66548260, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isopropylamine | HCID 6363 | — |
| Reactant | 4-Amino-1-Boc-piperidine | HCID 1268291 | — |
| Reactant | 2-(Methylthio)-4-(tributylstannyl)pyrimidine | HCID 2763261 | — |
| Reactant | 3-Bromo-8-chloroimidazo[1,2-a]pyrazine | HCID 10059849 | — |
| Product | HCID 66548260 | HCID 66548260 | — |
Reaction Steps
[3-(2-Isopropylamino-pyrimidin-4-yl)-imidazo[1,2-a]pyrazin-8-yl]-piperidin-4-yl-amine was prepared by a process analogous to that described in Example 12 starting from 3-bromo-8-chloro-imidazo[1,2-a]pyrazine (from Example 1 supra), 4-amino-piperidine-1-carboxylic acid tert-butyl ester, 2-methylsulfanyl-4-tributylstannanyl-pyrimidine, and isopropylamine. LC-MS: [M+H]+ 353.3.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08673905B2 |
| Source dataset | uspto-grants-2014_03 |
| ORD ID | ord-b795bc394df540a597c670bce34ef43d |
| Source note | uspto-grants-2014_03 |