4-Amino-N-(2-methylphenyl)benzenesulfonamide → HCID 43257398, compound

HRID 1186648Notes

Reaction equation

HRID 1186648 reaction equation
N[C:2]1C=CC(S(NC2C=CC=CC=2C)(=O)=O)=CC=1.[CH3:19][O:20][C:21]1[CH:26]=[C:25]([N+:27]([O-])=O)[CH:24]=[CH:23][C:22]=1[S:30]([NH:33][C:34]1[CH:39]=[CH:38][CH:37]=[CH:36][C:35]=1C)(=[O:32])=[O:31]>>[NH2:27][C:25]1[CH:24]=[CH:23][C:22]([S:30]([NH:33][C:34]2[CH:35]=[C:36]([CH3:2])[CH:37]=[CH:38][CH:39]=2)(=[O:31])=[O:32])=[C:21]([O:20][CH3:19])[CH:26]=1

Participants

3

Reactant 2

HCID 5935694-Amino-N-(2-methylphenyl)benzenesulfonamideHCID 47062662HCID 47062662, compound

Product 1

HCID 43257398HCID 43257398, compound

Procedure

(RK1-1-39) I This compound was prepared according to the procedure described for compound 12a except using 11h to obtain the required product as an orange-brown solid in (169 mg, 66%). Mp: not determined; 1H NMR (400 MHz, CDCl3) δ 7.50 (d, J=8.4 Hz, 1H), 6.99 (t, J=7.8 Hz, 1H), 6.82 (br s, 1H), 6.79-6.73 (m, 2H), 6.65 (br s, 1H), 6.11 (d, J=2.0 Hz, 1H), 6.09 (s, 1H), 3.99 (br s, 2H), 3.86 (s, 3H), 2.18 (s, 3H).

Workup

  1. custom(RK1-1-39) I This compound was prepared

Sources & evidence

ORD record
ord-911a739392f842ea997fffa9a4f9e5bc
Source dataset
uspto-grants-2014_03
Patent number
US08673910B2

Reaction notes

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