HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(3-chloro-1,4-dioxo-1,4-dihydro-naphthalen-2-ylamino)-2-methoxy-N-(4-methoxy-phenyl)-benzenesulfonamide → N-(3-(ethylthio)-4-hydroxynaphthalen-1-yl)thiophene-2-sulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(3-chloro-1,4-dioxo-1,4-dihydro-naphthalen-2-ylamino)-2-methoxy-N-(4-methoxy-phenyl)-benzenesulfonamide | HCID 49863871 | — |
| Reactant | N-(4-hydroxy-3-(1-methyl-1H-tetrazol-5-ylthio)naphthalen-1-yl)thiophene-2-sulfonamide | HCID 135895396 | — |
| Product | N-(3-(ethylthio)-4-hydroxynaphthalen-1-yl)thiophene-2-sulfonamide | HCID 46908186 | — |
Reaction Steps
5.2.52 N-(3-(ethylthio)-4-hydroxynaphthalen-1-yl)thiophene-2-sulfonamide (14j) was prepared according to the procedure for 14d except using (E)-N-(3-ethylthio-4-oxonaphthalen-1(4H)-ylidene)thiophene-2-sulfonamide (13j), which afforded the title compound 14 mg (100%) as a grey solid, m.p.: ° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08673910B2 |
| Source dataset | uspto-grants-2014_03 |
| ORD ID | ord-dad2a3fff621457c8310924536ec8cd9 |
| Source note | uspto-grants-2014_03 |