HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-{[1-Hydroxy-4-(thiophene-2-sulfonamido)naphthalen-2-yl]sulfanyl}acetic acid → 2-(4-(4,5-Dichlorothiophene-2-sulfonamido)-1-hydroxynaphthalen-2-ylthio)acetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-{[1-Hydroxy-4-(thiophene-2-sulfonamido)naphthalen-2-yl]sulfanyl}acetic acid | HCID 1582605 | — |
| Reactant | 4,5-dichloro-N-(3-chloro-4-oxonaphthalen-1(4H)-ylidene)thiophene-2-sulfonamide | HCID 67330668 | — |
| Product | 2-(4-(4,5-Dichlorothiophene-2-sulfonamido)-1-hydroxynaphthalen-2-ylthio)acetic acid | HCID 44609147 | — |
Reaction Steps
5.2.56 2-(4-(4,5-dichlorothiophene-2-sulfonamido)-1-hydroxynaphthalen-2-ylthio)acetic acid (14n) was prepared according to the procedure of procedure B for 10a except using 4,5-dichloro-N-(3-chloro-4-oxonaphthalen-1(4H)-ylidene)thiophenesulfonamide (12c), which afforded the title compound 17.8 mg (39%) as a white solid, m.p.: ° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08673910B2 |
| Source dataset | uspto-grants-2014_03 |
| ORD ID | ord-38f9fabba7604306a2035cddb7d05f9e |
| Source note | uspto-grants-2014_03 |