HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl Thioglycolate → Ethyl 2-(4-(biphenyl-4-ylsulfonamido)-1-hydroxynaphthalen-2-ylthio)acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl Thioglycolate | HCID 12185 | — |
| Reactant | 2-{[1-Hydroxy-4-(thiophene-2-sulfonamido)naphthalen-2-yl]sulfanyl}acetic acid | HCID 1582605 | — |
| Reactant | (NE)-N-(3-chloro-4-oxonaphthalen-1-ylidene)-4-phenylbenzenesulfonamide | HCID 58398230 | — |
| Product | Ethyl 2-(4-(biphenyl-4-ylsulfonamido)-1-hydroxynaphthalen-2-ylthio)acetate | HCID 46908188 | — |
Reaction Steps
5.2.60 Ethyl 2-(4-(biphenyl-4-ylsulfonamido)-1-hydroxynaphthalen-2-ylthio)acetate (14r) was prepared according to the procedure of procedure B for 10a except using (E)-N-(3-chloro-4-oxonaphthalen-1(4H)-ylidene)biphenyl-4-sulfonamide (12b) and ethyl mercapto-acetate, which afforded the title compound 71.5 mg (85.5%) as an off-white solid, m.p.: 166-168° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08673910B2 |
| Source dataset | uspto-grants-2014_03 |
| ORD ID | ord-bd01724a34da4290abd69cf478810e87 |
| Source note | uspto-grants-2014_03 |