HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-{[1-Hydroxy-4-(thiophene-2-sulfonamido)naphthalen-2-yl]sulfanyl}acetic acid → 2-(1-Hydroxy-4-(naphthalene-2-sulfonamido)naphthalen-2-ylthio)propanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-{[1-Hydroxy-4-(thiophene-2-sulfonamido)naphthalen-2-yl]sulfanyl}acetic acid | HCID 1582605 | — |
| Reactant | (NE)-N-(3-chloro-4-oxonaphthalen-1-ylidene)naphthalene-2-sulfonamide | HCID 24282891 | — |
| Reactant | HCID 178473673 | HCID 178473673 | — |
| Product | 2-(1-Hydroxy-4-(naphthalene-2-sulfonamido)naphthalen-2-ylthio)propanoic acid | HCID 16482413 | — |
Reaction Steps
5.2.64 2-(1-hydroxy-4-(naphthalene-2-sulfonamido)naphthalen-2-ylthio)propanoic acid (14v) was prepared according to the procedure of procedure B for 10a except using thiolactic acid and (E)-N-(3-chloro-4-oxonaphthalen-1(4H)-ylidene)naphthalene-2-sulfonamide (12f), which afforded the title compound 51.3 mg (58.6%) as an off-white solid, m.p.: 176-178° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08673910B2 |
| Source dataset | uspto-grants-2014_03 |
| ORD ID | ord-23c2275f2c694d5fa2a383cdc3e30a0c |
| Source note | uspto-grants-2014_03 |