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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 118671Generated: October 25, 2026

Dimethylformamide → 5-Amino-N-{2-[({[2-chloro-6-(trifluoromethyl)phenyl]carbonyl}amino)methyl]-3,3,3-trifluoro-2-hydroxypropyl}-1-(4-fluorophenyl)-1H-pyrazole-4-carboxamide

https://huagongshe.com/reaction/118671

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
ReactantTetrahydrofuranHCID 8028—
ReactantOxalyl chlorideHCID 65578—
ReactantDiisopropylethylamineHCID 81531—
Reactant2-chloro-6-(trifluoromethyl)benzoic AcidHCID 11127965—
Reactant5-amino-N-[2-(aminomethyl)-3,3,3-trifluoro-2-hydroxypropyl]-1-(4-fluorophenyl)-1H-pyrazole-4-carboxamideHCID 59487494—
Product5-Amino-N-{2-[({[2-chloro-6-(trifluoromethyl)phenyl]carbonyl}amino)methyl]-3,3,3-trifluoro-2-hydroxypropyl}-1-(4-fluorophenyl)-1H-pyrazole-4-carboxamideHCID 59487488—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
ORD IDord-ce6000fba8064810b189c3845b9876aa
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (2/10)