Sodium Bicarbonate → HCID 86690017, compound

Participants

Reaction Steps

To an anhydrous dichloromethane (8 mL) suspension of 4-(4-methoxyphenyl)-1,4-dihydrobenzo[f]quinoxaline-2,3-dione (200 mg, 0.63 mmol) was added a 1M boron tribromide/dichloromethane solution (0.94 mL, 0.94 mmol) under cooling in an ice-bath. The mixture was stirred at room temperature for 18 hours. The reaction mixture was poured into a saturated aqueous sodium hydrogen carbonate solution. The precipitated solid was washed with water and ethanol. The solid was further washed with hexane, and dried to obtain the titled compound as a off-white crystal (285 mg, yield 45%).

Provenance & Evidence