Pyridine-3-sulfonyl chloride → HCID 86690030, compound

HRID 1186755Notes

Reaction equation

HRID 1186755 reaction equation
[NH2:1][C:2]1[CH:3]=[C:4]([N:8]2[C:17]3[CH:16]=[CH:15][C:14]4[CH2:18][CH2:19][CH2:20][CH2:21][C:13]=4[C:12]=3[NH:11][C:10](=[O:22])[C:9]2=[O:23])[CH:5]=[CH:6][CH:7]=1.[N:24]1[CH:29]=[CH:28][CH:27]=[C:26]([S:30]([Cl:33])(=[O:32])=[O:31])[CH:25]=1>>[ClH:33].[O:22]=[C:10]1[NH:11][C:12]2[C:13]3[CH2:21][CH2:20][CH2:19][CH2:18][C:14]=3[CH:15]=[CH:16][C:17]=2[N:8]([C:4]2[CH:3]=[C:2]([NH:1][S:30]([C:26]3[CH:25]=[N:24][CH:29]=[CH:28][CH:27]=3)(=[O:32])=[O:31])[CH:7]=[CH:6][CH:5]=2)[C:9]1=[O:23]

Participants

3

Reactant 2

HCID 3164136Pyridine-3-sulfonyl chlorideHCID 56640367HCID 56640367, compound

Product 1

HCID 86690030HCID 86690030, compoundYield 26%

Procedure

4-(3-Aminophenyl)-1,4,7,8,9,10-hexahydrobenzo[f]quinoxaline-2,3-dione (30 mg, 0.097 mmol) and 3-pyridinesulfonyl chloride (26 mg, 0.146 mmol) were used in a process similar to Example 9 to give the titled compound (a white crystal, 12 mg, yield 26%).

Sources & evidence

ORD record
ord-3135dab3cfbc46d1a3f5c45058e3eb0e
Source dataset
uspto-grants-2014_03
Patent number
US08673915B2

Reaction notes

Loading…