HuagongsheHuagongshe Chemistry Print Report · For research reference only
Glyoxylic Acid → HCID 10775091, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Glyoxylic Acid | HCID 760 | — |
| Reactant | Hydrazine hydrate (1:1) | HCID 24654 | — |
| Reactant | 1-(p-Methoxyphenyl)-2-propanone | HCID 31231 | — |
| Product | HCID 10775091 | HCID 10775091 | — |
Reaction Steps
5-Aryl pyridazinone examples were synthesized as outlined in Schemes 7 and 8. Condensation of 4-methoxyphenyl acetone (R14=Me) with glyoxylic acid (Scheme 7), followed by cyclization with hydrazine hydrate or N-substituted hydrazine derivatives afforded 5-(4-methoxy-phenyl)-6-methyl-2H-pyridazin-3-one, and N—R12 examples (Farmaco, 1987, 43, 539).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08673916B2 |
| Source dataset | uspto-grants-2014_03 |
| ORD ID | ord-226725012678463fa6bff593e7eebed2 |
| Source note | uspto-grants-2014_03 |