Trifluoroacetic acid → HCID 59568680, compound

Participants

Reaction Steps

To a solution of 1,1-dimethylethyl-4-{[6-bromo-7-(methyloxy)-3,4-dihydro-1H-isochromen-1-yl]methyl}piperazine-1-carboxylate (150 mg, 0.34 mmol) in 5 mL of DCM was added 5 mL of TFA and the mixture was stirred at room temperature for 1 h. The reaction was concentrated and the 1-{[6-bromo-7-(methyloxy)-3,4-dihydro-1H-isochromen-1-yl]methyl}piperazine was directly used in next step.

Provenance & Evidence