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HRID1187106

反应详情

EQUATION

反应方程式

HRID 1187106 的结构方程式

REACTANTS

反应物

2
结构：Cc1c([C@@H]2CO2)ccc2c1COC2=O
HCID59568646

4-Methyl-5-[(2R)-oxiran-2-yl]-2-benzofuran-1(3H)-one

C11H10O3

结构：Cc1c(CCN2CCNCC2)ccc2c1COC2=O
HCID59568688

未命名化合物

PRODUCTS

生成物

1
结构：Cc1c(CCN2CCN(C[C@H](O)c3ccc4c(c3C)COC4=O)CC2)ccc2c1COC2=O
HCID49804480

未命名化合物

PROCEDURE

实验过程

5-((1R)-1-hydroxy-2-{4-[2-(4-methyl-1-oxo-1,3-dihydro-2-benzofuran-5-yl)ethyl]piperazin-1-yl}ethyl)-4-methyl-2-benzofuran-1(3H)-one was prepared in a similar fashion to that described for the synthesis of EXAMPLE 12 starting from 4-methyl-5-[(2R)-oxiran-2-yl]-2-benzofuran-1(3H)-one and 4-methyl-5-(2-piperazin-1-ylethyl)-2-benzofuran-1(3H)-one.