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HRID1187154

反应详情

EQUATION

反应方程式

HRID 1187154 的结构方程式

REACTANTS

反应物

2
结构：N#Cc1cnc(C2CO2)c(Cl)c1
HCID59568719

未命名化合物

结构：Cc1c([C@@H](O)CN2CCNCC2)ccc2c1COC2=O
HCID59568728

未命名化合物

PRODUCTS

生成物

1
结构：Cc1c([C@@H](O)CN2CCN(CC(O)c3ncc(C#N)cc3Cl)CC2)ccc2c1COC2=O
HCID49802222

未命名化合物

PROCEDURE

实验过程

5-Chloro-6-[1-hydroxy-2-[4-[(2R)-2-hydroxy-2-(4-methyl-1-oxo-3H-isobenzofuran-5-yl)ethyl]piperazin-1-yl]ethyl]pyridine-3-carbonitrile was prepared in a similar fashion to that described for the synthesis of EXAMPLE 58 starting from 5-[(1R)-1-hydroxy-2-(piperazin-1-yl)ethyl]-4-methyl-2-benzofuran-1(3H)-one and 5-chloro-6-(oxiran-2-yl)pyridine-3-carbonitrile.