HuagongsheHuagongshe Chemistry Print Report · For research reference only
8-Phenyloctanoic acid → HCID 66875254, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 8-Phenyloctanoic acid | HCID 520273 | — |
| Reactant | (R)-benzyl 3-amino-4-(dimethylamino)butanoate dihydrochloride | HCID 46223507 | — |
| Product | HCID 66875254 | HCID 66875254 | — |
Reaction Steps
The title compound, m/e=347.4 ([M−H]−), was produced in analogy with intermediate 1, steps 3 and 4. Thus, commercially available 8-phenyloctanoic acid was coupled in step 3 with (R)-3-amino-4-dimethylamino-butyric acid benzyl ester dihydrochloride to produce (R)-4-dimethylamino-3-(8-phenyl-octanoylamino)-butyric acid benzyl ester, which was hydrogenated in step 4.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08673946B2 |
| Source dataset | uspto-grants-2014_03 |
| ORD ID | ord-b1c3dd0c0cbe4be78f61cff95964f0b9 |
| Source note | uspto-grants-2014_03 |