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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1188253Generated: November 2, 2026

tert-Butoxycarbonyl-L-isoleucine → HCID 58434130, compound

https://huagongshe.com/reaction/1188253

Reaction equation

Participants

RoleNameHCIDCharge
Reactanttert-Butoxycarbonyl-L-isoleucineHCID 2724762—
Reactant(-)-DidesmethylsibutramineHCID 9794968—
ProductHCID 58434130HCID 58434130—

Reaction Steps

By similar method as example 2, resolved (S)-1-[1-(4-chlorophenyl)cyclobutyl]-3-methylbutylamine (II-S) (250 mg) was condensed with Boc-L-isoleucine (210 mg) to give the title compound (2S,3S)-2-(Boc-amino)-N-{(S)-1-[1-(4-chlorophenyl)cyclobutyl]-3-methylbutyl}-3-methylvaleramide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08673981B2
Source datasetuspto-grants-2014_03
ORD IDord-b4dba222d4d348d7bf6955c3d8d1ffe4
Source noteuspto-grants-2014_03