HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Chloro-2-fluoro-5-(trifluoromethyl)benzoic acid → 1-({5-[3-Chloro-2-fluoro-5-(trifluoromethyl)phenyl]-1,2,4-oxadiazol-3-yl}methyl)-4-(trifluoromethyl)-1H-indole-5-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Chloro-2-fluoro-5-(trifluoromethyl)benzoic acid | HCID 2773751 | — |
| Reactant | HCID 178509476 | HCID 178509476 | — |
| Product | 1-({5-[3-Chloro-2-fluoro-5-(trifluoromethyl)phenyl]-1,2,4-oxadiazol-3-yl}methyl)-4-(trifluoromethyl)-1H-indole-5-carbonitrile | HCID 24983990 | — |
Reaction Steps
Synthesized as described in Example 65 from 2-[5-cyano-4-(trifluoromethyl)-1H-indol-1-yl]-N-hydroxyethanimidamide and 3-chloro-2-fluoro-5-(trifluoromethyl)benzoic acid: MS (ESI): m/z 487 (M−1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08673948B2 |
| Source dataset | uspto-grants-2014_03 |
| ORD ID | ord-1d8a153599fc485fa29be2c172763803 |
| Source note | uspto-grants-2014_03 |