HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Methoxy-3-(trifluoromethyl)benzoyl chloride → 1-({5-[4-(Methyloxy)-3-(trifluoromethyl)phenyl]-1,2,4-oxadiazol-3-yl}methyl)-4-(trifluoromethyl)-1H-indole-5-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Methoxy-3-(trifluoromethyl)benzoyl chloride | HCID 2775298 | — |
| Reactant | HCID 178509476 | HCID 178509476 | — |
| Product | 1-({5-[4-(Methyloxy)-3-(trifluoromethyl)phenyl]-1,2,4-oxadiazol-3-yl}methyl)-4-(trifluoromethyl)-1H-indole-5-carbonitrile | HCID 24983992 | — |
Reaction Steps
Synthesized as described in Example 70 from 2-[5-cyano-4-(trifluoromethyl)-1H-indol-1-yl]-N-hydroxyethanimidamide and 4-(methyloxy)-3-(trifluoromethyl)benzoyl chloride. MS (ESI): m/z 467 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08673948B2 |
| Source dataset | uspto-grants-2014_03 |
| ORD ID | ord-c6f07896adcd4afaba2549b694251e69 |
| Source note | uspto-grants-2014_03 |