3-Cyanobenzoic acid → HCID 24984144, compound

HRID 1188375Notes

Reaction equation

HRID 1188375 reaction equation
[C:1]([C:3]1[C:4]([C:17]([F:20])([F:19])[F:18])=[C:5]2[C:9](=[CH:10][CH:11]=1)[N:8]([CH2:12][C:13](=[NH:16])[NH:14][OH:15])[CH:7]=[CH:6]2)#[N:2].[C:21]([C:23]1[CH:24]=[C:25]([CH:29]=[CH:30][CH:31]=1)[C:26](O)=O)#[N:22]>>[C:21]([C:23]1[CH:24]=[C:25]([C:26]2[O:15][N:14]=[C:13]([CH2:12][N:8]3[C:9]4[C:5](=[C:4]([C:17]([F:19])([F:20])[F:18])[C:3]([C:1]#[N:2])=[CH:11][CH:10]=4)[CH:6]=[CH:7]3)[N:16]=2)[CH:29]=[CH:30][CH:31]=1)#[N:22]

Participants

3

Reactant 2

HCID 158753-Cyanobenzoic acidHCID 178509476HCID 178509476, compound

Product 1

HCID 24984144HCID 24984144, compound

Procedure

Synthesized as described in Example 72 from 2-[5-cyano-4-(trifluoromethyl)-1H-indol-1-yl]-N-hydroxyethanimidamide and 3-cyanobenzoic acid: MS (ESI): m/z 392 (M−1).

Workup

  1. customSynthesized

Sources & evidence

ORD record
ord-de91bfe5f00f4515b9846ae69ed9c123
Source dataset
uspto-grants-2014_03
Patent number
US08673948B2

Reaction notes

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