HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(Chloromethyl)-5-(4-methoxyphenyl)-1,2,4-oxadiazole → 1-({5-[4-(Methyloxy)phenyl]-1,2,4-oxadiazol-3-yl}methyl)-4-(trifluoromethyl)-1H-indole-5-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(Chloromethyl)-5-(4-methoxyphenyl)-1,2,4-oxadiazole | HCID 2797131 | — |
| Reactant | 4-(trifluoromethyl)-1H-indole-5-carbonitrile | HCID 67405449 | — |
| Product | 1-({5-[4-(Methyloxy)phenyl]-1,2,4-oxadiazol-3-yl}methyl)-4-(trifluoromethyl)-1H-indole-5-carbonitrile | HCID 24984456 | — |
Reaction Steps
Synthesized as described in Example 23 using 4-(trifluoromethyl)-1H-indole-5-carbonitrile and 3-(chloromethyl)-5-[4-(methyloxy)phenyl]-1,2,4-oxadiazole: MS (ES) m/z 399 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08673948B2 |
| Source dataset | uspto-grants-2014_03 |
| ORD ID | ord-cbc8c03b796248b4992a4bce47ccbd55 |
| Source note | uspto-grants-2014_03 |