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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1188404Generated: October 26, 2026

Picolinohydrazide → 1-{[5-(2-Pyridinyl)-1,3,4-oxadiazol-2-yl]methyl}-4-(trifluoromethyl)-1H-indole-5-carbonitrile

https://huagongshe.com/reaction/1188404

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPicolinohydrazideHCID 255881—
Reactant[5-cyano-4-(trifluoromethyl)-1H-indol-1-yl]acetic acidHCID 57800132—
Product1-{[5-(2-Pyridinyl)-1,3,4-oxadiazol-2-yl]methyl}-4-(trifluoromethyl)-1H-indole-5-carbonitrileHCID 24984780—

Reaction Steps

Synthesized as described in Example 35C from [5-cyano-4-(trifluoromethyl)-1H-indol-1-yl]acetic acid and 2-pyridinecarbohydrazide: MS (ES) m/z 370 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08673948B2
Source datasetuspto-grants-2014_03
ORD IDord-9b4ed415fd494926aebcb052bd643731
Source noteuspto-grants-2014_03