4-Methyl-1,2,3-thiadiazole-5-carbohydrazide → 1-{[5-(4-Methyl-1,2,3-thiadiazol-5-yl)-1,3,4-oxadiazol-2-yl]methyl}-4-(trifluoromethyl)-1H-indole-5-carbonitrile

Participants

Role	Name	HCID	Charge
Reactant	4-Methyl-1,2,3-thiadiazole-5-carbohydrazide	HCID 1419752	—
Reactant	[5-cyano-4-(trifluoromethyl)-1H-indol-1-yl]acetic acid	HCID 57800132	—
Product	1-{[5-(4-Methyl-1,2,3-thiadiazol-5-yl)-1,3,4-oxadiazol-2-yl]methyl}-4-(trifluoromethyl)-1H-indole-5-carbonitrile	HCID 57800159	—

Reaction Steps

Synthesized as described in Example 35C from [5-cyano-4-(trifluoromethyl)-1H-indol-1-yl]acetic acid and 4-methyl-1,2,3-thiadiazole-5-carbohydrazide: MS (ES) m/z 391 (M+1).

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08673948B2
Source dataset	uspto-grants-2014_03
ORD ID	ord-e99247e16c534d97b051ce3d10b017d5
Source note	uspto-grants-2014_03