HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,5-Difluorobenzohydrazide → 1-{[5-(2,5-Difluorophenyl)-1,3,4-oxadiazol-2-yl]methyl}-4-(trifluoromethyl)-1H-indole-5-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,5-Difluorobenzohydrazide | HCID 2774074 | — |
| Reactant | [5-cyano-4-(trifluoromethyl)-1H-indol-1-yl]acetic acid | HCID 57800132 | — |
| Product | 1-{[5-(2,5-Difluorophenyl)-1,3,4-oxadiazol-2-yl]methyl}-4-(trifluoromethyl)-1H-indole-5-carbonitrile | HCID 57800271 | — |
Reaction Steps
Synthesized as described in Example 35C from [5-cyano-4-(trifluoromethyl)-1H-indol-1-yl]acetic acid and 2,5-difluorobenzohydrazide: MS (ES) m/z 405 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08673948B2 |
| Source dataset | uspto-grants-2014_03 |
| ORD ID | ord-22ad36f7989044daabc222fc6eda7f48 |
| Source note | uspto-grants-2014_03 |