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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1188507생성일: 2026년 10월 25일

4-(Chloromethyl)-1,3-thiazole hydrochloride → 4-Chloro-1-(1,3-thiazol-4-ylmethyl)-2-(trifluoromethyl)-1H-benzimidazole-5-carbonitrile

https://huagongshe.com/reaction/1188507

반응식

참여 물질

역할이름HCID투입량
반응물4-(Chloromethyl)-1,3-thiazole hydrochlorideHCID 2763289—
반응물4-chloro-2-(trifluoromethyl)-1H-benzimidazole-5-carbonitrileHCID 67404532—
생성물4-Chloro-1-(1,3-thiazol-4-ylmethyl)-2-(trifluoromethyl)-1H-benzimidazole-5-carbonitrileHCID 67405446—

반응 단계

Synthesized as described in Example 197B from 4-chloro-2-(trifluoromethyl)-1H-benzimidazole-5-carbonitrile and 4-(chloromethyl)-1,3-thiazole hydrochloride: MS (ESI) m/z 343 (M+1).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08673948B2
출처 데이터셋uspto-grants-2014_03
ORD IDord-231e71b80e1e4cccb1b77bc2b810194a
출처 메모uspto-grants-2014_03