HuagongsheHuagongshe Chemistry Print Report · For research reference only
Bromine → HCID 57800275, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Bromine | HCID 24408 | — |
| Reactant | N-(3-chloro-2-methylphenyl)-2,2-dimethylpropanamide | HCID 4204423 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | HCID 57800275 | HCID 57800275 | — |
Reaction Steps
N-(3-Chloro-2-methylphenyl)-2,2-dimethylpropanamide (0.5 g, 2.2 mmol) and bromine (1.4 g, 8.8 mmol) were combined in AcOH (25 mL) at rt for 2 h. The residue resulting from concentration was purified by flash chromatography (20-60% EtOAc-hexanes gradient) to afford the title compound: MS (ES) m/z 305 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08673948B2 |
| Source dataset | uspto-grants-2014_03 |
| ORD ID | ord-7bc23d51995844d293c8452c6f57d5b4 |
| Source note | uspto-grants-2014_03 |