3-(Chloromethyl)-5-[3-(trifluoromethyl)phenyl]-1,2,4-oxadiazole → HCID 57800067, compound

Participants

Reaction Steps

Synthesized as described in Example 4 from 4-chloro-2-(3,3,3-trifluoropropyl)-1H-indole-5-carbonitrile and 3-(chloromethyl)-5-[3-(trifluoromethyl)phenyl]-1,2,4-oxadiazole: 1H NMR (400 MHz, CDCl3) δ 8.31 (s, 1H), 8.23 (d, J=7.8 Hz, 1H), 7.86 (d, J=7.9 Hz, 1 H), 7.67 (dd, J=7.8 Hz, 1H), 7.45 (s, 2H), 6.56 (s, 1H), 5.45 (s, 2H), 3.27 (t, 2H), 2.89-2.61 (m, 2H); MS (ES) m/z 499 (M+1).

Provenance & Evidence